Solute Carriers and drug transport

In humans, membrane proteins that help absorb nutrients are also key for transporting drugs to specific organs like the brain, liver, kidneys, and digestive system. Understanding how these nutrient transporters work is important because they significantly affect how drugs behave in the body, offering clear medical benefits such as reduced side effects, reduction in dosage and organ toxicity.

We study various types of nutrient transporters that control how cells take in peptides, amino acids, vitamins, sugars, and lipids. These systems are also crucial for the absorption of drugs like antibiotics, anticancer agents, anti-inflammatories, and steroids. Our research aims to understand how drugs and nutrients are recognized and transported, aiding drug development and identifying new targets in human disease.

Below are our latest publications in this research area.