Recent research publications

Review articles can be found here.

2016-2019

Parker JL, Corey R, Stansfeld P, Newstead S. (2019) Structural basis for substrate specificity and regulation of nucleotide sugar transporters in the lipid bilayer. Nature Communications.

Zhiyi W, Alibay I, Newstead S, Biggin PC. (2019) Proton control transitions in an amino acid transporters. Biophysical Journal.

Bräuer P, Parker JL, Gerondopoulos A, Zimmermann I, Seeger MA, Barr FA, Newstead S. (2019) Structural basis for pH-dependent retrieval of ER proteins from the Golgi by the KDEL receptor. Science

Minhas GS, Newstead S. (2019) Structural basis for prodrug recognition by the SLC15 family of proton coupled peptide transporters. PNAS.

Minhas GS, Bawdon D, Herman R, Rudden M, Stone AP, James AG, Thomas GH, Newstead S. (2018) Structural basis of malodour precursor transport in the human axillaeLIFE

McIlwain BC, Newstead S, Stockbridge RB. (2018) Cork-in-Bottle Occlusion of Fluoride Ion Channels by Crystallization Chaperones. Structure

Jungnickel, EJK, Parker JL, Newstead S. (2018) Structural basis for amino acid transport by the CAT family of SLC7 transporters. Nature Communications

Parker JL, Newstead S. (2017) Structural basis of nucleotide sugar transport across the Golgi membrane. Nature

Parker JL, Li C, Brinth A, Wang Z, Vogeley L, Solcan N, Ledderboge-Vucinic G, Swanson JMJ, Caffrey M, Voth GA, Newstead S. (2017) Proton movement and coupling in the POT family of peptide transporters. PNAS.

Newstead S. (2017) Recent advances in understanding proton coupled peptide transport via the POT family. Curr. Opin. Struct. Biol.

Newstead S. (2017) Symmetry and Structure in the POT Family of Proton Coupled Peptide Transporters. Symmetry.

Byrne EF, Sircar R, Miller PS, Hedger G, Luchetti G, Nachtergaele S, Tully MD, Mydock-McGrane L, Covey DF, Rambo RP, Sansom MS, Newstead S, Rohatgi R, Siebold, C. (2016) Structural basis of Smoothened regulation by its extracellular domains. Nature

Zhang F, Hanson SM, Jara-Oseguera A, Krepkiy D, Bae C, Pearce LV, Blumberg PM, Newstead S, Swartz KJ. (2016) Engineering vanilloid-sensitivity into the rat TRPV2 channel. eLife

Samsudin F, Parker JL, Sansom MS, Newstead S, Fowler PW. (2016) Accurate prediction of ligand affinities for a peptide transporter. Cell Chemistry & Biology.

Parker JL, Newstead S. (2016) Membrane Protein Crystallisation: Current Trends and Future Perspectives. Adv. Exp. Med. Biol.